This baked macaroni and cheese recipe laughs at boxed mac and cheese and scoffs at powder. Its always been my favorite and every year she makes it at family gatherings and its the one dish, along with my mother in laws potato salad, that I could live off during the feast. Our Nana makes the best baked homemade mac and cheese this side of the south. But not with Nana’s mac and cheese recipe. I’ve suffered through countless crock pots full while telling people how great it is, but all the time waiting to throw my plate out.